BDBM50305395 1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(4-fluorobenzyl)-1H-pyrazole-3-carboxamide::CHEMBL594655

SMILES Fc1ccc(CNC(=O)c2nn(c(c2CC#N)-c2ccc(Cl)cc2)-c2ccccc2Cl)cc1

InChI Key InChIKey=QAKDNMTUXGFHFX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305395   

TargetCannabinoid receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50305395(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanometh...)
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP-55940-induced GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50305395(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanometh...)
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed