BDBM50304983 (S)-4-((1-acetylpyrrolidin-3-yl)(2-(trifluoromethyl)benzyl)amino)-2-chlorobenzonitrile::CHEMBL590611

SMILES CC(=O)N1CC[C@@H](C1)N(Cc1ccccc1C(F)(F)F)c1ccc(C#N)c(Cl)c1

InChI Key InChIKey=JRMYTEMFHGPYNN-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50304983   

TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304983((S)-4-((1-acetylpyrrolidin-3-yl)(2-(trifluoromethy...)
Affinity DataEC50:  35nMAssay Description:Agonist activity at PR in human T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304983((S)-4-((1-acetylpyrrolidin-3-yl)(2-(trifluoromethy...)
Affinity DataIC50: 30nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304983((S)-4-((1-acetylpyrrolidin-3-yl)(2-(trifluoromethy...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304983((S)-4-((1-acetylpyrrolidin-3-yl)(2-(trifluoromethy...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed