BDBM50304976 (S)-methyl 3-((3-chloro-4-cyanophenyl)(2-fluorobenzyl)amino)pyrrolidine-1-carboxylate::CHEMBL592289

SMILES COC(=O)N1CC[C@@H](C1)N(Cc1ccccc1F)c1ccc(C#N)c(Cl)c1

InChI Key InChIKey=PSCZYTUSQHDICG-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50304976   

TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304976((S)-methyl 3-((3-chloro-4-cyanophenyl)(2-fluoroben...)
Affinity DataEC50:  165nMAssay Description:Agonist activity at PR in human T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304976((S)-methyl 3-((3-chloro-4-cyanophenyl)(2-fluoroben...)
Affinity DataIC50: 12nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304976((S)-methyl 3-((3-chloro-4-cyanophenyl)(2-fluoroben...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304976((S)-methyl 3-((3-chloro-4-cyanophenyl)(2-fluoroben...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed