BDBM50303997 2-Benzyl-4-(4-methylpiperazin-1-yl)-1H-benzimidazole::CHEMBL566410

SMILES CN1CCN(CC1)c1cccc2[nH]c(Cc3ccccc3)nc12

InChI Key InChIKey=XNQNBYVDOBUBNO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303997   

Target5-hydroxytryptamine receptor 6(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50303997(2-Benzyl-4-(4-methylpiperazin-1-yl)-1H-benzimidazo...)
Affinity DataKi:  16nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of serotonin-induced cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50303997(2-Benzyl-4-(4-methylpiperazin-1-yl)-1H-benzimidazo...)
Affinity DataKi:  66.8nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50303997(2-Benzyl-4-(4-methylpiperazin-1-yl)-1H-benzimidazo...)
Affinity DataKi: >500nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed