BDBM50303905 (4E,4'E)-4,4'-bis(pentan-3-ylimino)-4',4'a-dihydro-2,2'-binaphthyl-1,1'(4H,8'aH)-dione::CHEMBL571208

SMILES CCC(CC)Nc1cc(C2=CC(=NC(CC)CC)c3ccccc3C2=O)c(O)c2ccccc12

InChI Key InChIKey=PCAOKQXIIIDCTJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50303905   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303905((4E,4'E)-4,4'-bis(pentan-3-ylimino)-4',4'a-dihydro...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant IDO expressed in HEK293 cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303905((4E,4'E)-4,4'-bis(pentan-3-ylimino)-4',4'a-dihydro...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mouse recombinant TDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303905((4E,4'E)-4,4'-bis(pentan-3-ylimino)-4',4'a-dihydro...)
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303905((4E,4'E)-4,4'-bis(pentan-3-ylimino)-4',4'a-dihydro...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of mouse recombinant IDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed