BDBM50303801 CHEMBL571546::N-benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetamide

SMILES O=C(Cc1ccc(cn1)-c1ccc(OCCN2CCOCC2)cc1)NCc1ccccc1

InChI Key InChIKey=HUNGUWOZPQBXGX-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50303801   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303801(N-benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303801(N-benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridi...)
Affinity DataIC50: 20nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303801(N-benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridi...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303801(N-benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridi...)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of Src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303801(N-benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridi...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human c-SRC expressed in mouse NIH/3T3 cells assessed as inhibition of cell growth in presence of 1.5% FCS by BrdU incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303801(N-benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridi...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human c-SRC expressed in mouse NIH/3T3 cells assessed as inhibition of cell growth in presence of 0.5% FCSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Athenex

Curated by ChEMBL
LigandPNGBDBM50303801(N-benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridi...)
Affinity DataIC50: 100nMAssay Description:Inhibition of LYN (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandPNGBDBM50303801(N-benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridi...)
Affinity DataIC50: 100nMAssay Description:Inhibition of BCR/ABL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed