BDBM50303417 4-(Cyclopentylamino)-6-(3,5-difluorophenylamino)-1,3,5-triazine-2-carbonitrile::CHEMBL568171

SMILES Fc1cc(F)cc(Nc2nc(NC3CCCC3)nc(n2)C#N)c1

InChI Key InChIKey=YKFSGPSMOHAYEG-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50303417   

TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303417(4-(Cyclopentylamino)-6-(3,5-difluorophenylamino)-1...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain after 5 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303417(4-(Cyclopentylamino)-6-(3,5-difluorophenylamino)-1...)
Affinity DataIC50: 63nMAssay Description:Inhibition of Trypanosoma cruzi cruzain after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTissue-type plasminogen activator(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303417(4-(Cyclopentylamino)-6-(3,5-difluorophenylamino)-1...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human tPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303417(4-(Cyclopentylamino)-6-(3,5-difluorophenylamino)-1...)
Affinity DataIC50: 8.13E+3nMAssay Description:Inhibition of human Caspase 4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-5(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303417(4-(Cyclopentylamino)-6-(3,5-difluorophenylamino)-1...)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of human Caspase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-6(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303417(4-(Cyclopentylamino)-6-(3,5-difluorophenylamino)-1...)
Affinity DataIC50: 3.55E+3nMAssay Description:Inhibition of human Caspase 6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-14(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303417(4-(Cyclopentylamino)-6-(3,5-difluorophenylamino)-1...)
Affinity DataIC50: 9.12E+3nMAssay Description:Inhibition of human Caspase 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPapain(Papaya)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303417(4-(Cyclopentylamino)-6-(3,5-difluorophenylamino)-1...)
Affinity DataIC50: 389nMAssay Description:Inhibition of papaya papainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin Z(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303417(4-(Cyclopentylamino)-6-(3,5-difluorophenylamino)-1...)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human Cathepsin X/ZMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed