BDBM50303006 CHEMBL517247::mulberrofuran D

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])ccc2cc(oc12)-c1cc(-[#8])cc(-[#8])c1-[#6]\[#6]=[#6](\[#6])-[#6]

InChI Key InChIKey=NADFUVMMBGOZIU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50303006   

TargetPancreatic triacylglycerol lipase(Pig)
Catholic University of Daegu

Curated by ChEMBL
LigandPNGBDBM50303006(mulberrofuran D | CHEMBL517247)
Affinity DataIC50: 90nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50303006(mulberrofuran D | CHEMBL517247)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Korean Research Institute of Biosciences and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50303006(mulberrofuran D | CHEMBL517247)
Affinity DataIC50: 4.05E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha protein accumulation in human Hep3B cells treated for 30 mins measured after 12 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
Korean Research Institute of Biosciences and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50303006(mulberrofuran D | CHEMBL517247)
Affinity DataIC50: 8.76E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human Hep3B cells by pGL3-HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50303006(mulberrofuran D | CHEMBL517247)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50303006(mulberrofuran D | CHEMBL517247)
Affinity DataIC50: 3.74E+3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed