BDBM50302608 (3S,4R,5R,6S)-2-(benzyloxy)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triol::CHEMBL567778

SMILES CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2OC(OCc3ccccc3)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key InChIKey=QKEQDXYUUYYDDR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302608   

TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302608((3S,4R,5R,6S)-2-(benzyloxy)-6-(4-chloro-3-(4-ethox...)
Affinity DataIC50: 620nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302608((3S,4R,5R,6S)-2-(benzyloxy)-6-(4-chloro-3-(4-ethox...)
Affinity DataIC50: 330nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed