BDBM50302606 (2S,3R,4R,5R)-2-[4-Chloro-3-(4-ethoxy-benzyl)-phenyl]-5-fluoro-6-methoxy-tetrahydro-pyran-3,4-diol::CHEMBL566940

SMILES CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2OC(OC)[C@H](F)[C@H](O)[C@H]2O)cc1

InChI Key InChIKey=JFVIJDSBSHXAJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302606   

TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302606((2S,3R,4R,5R)-2-[4-Chloro-3-(4-ethoxy-benzyl)-phen...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302606((2S,3R,4R,5R)-2-[4-Chloro-3-(4-ethoxy-benzyl)-phen...)
Affinity DataIC50: 220nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed