BDBM50302114 CHEMBL569817::N-(4-chloro-3-(pyrazolo[1,5-a]pyridin-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide

SMILES Cc1nc(ccc1C(=O)Nc1ccc(Cl)c(c1)-c1cc2ccccn2n1)C(F)(F)F

InChI Key InChIKey=OFYSCZLGXWEMMT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50302114   

TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302114(N-(4-chloro-3-(pyrazolo[1,5-a]pyridin-2-yl)phenyl)...)
Affinity DataIC50: 170nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed