BDBM50301366 5-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyridin-2-yl)-2-oxo-1-phenyl-1,2-dihydropyridine-3-carboxamide::CHEMBL570369

SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4cc(Cc5ccccc5)cn(-c5ccccc5)c4=O)nc3)c2cc1OC

InChI Key InChIKey=SEJFSSIRSRIMHC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50301366   

TargetProtein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50301366(5-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...)
Affinity DataIC50: 310nMAssay Description:Inhibition of human PyK2 Y402 autophosphorylation expressed in 293T cells by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50301366(5-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50301366(5-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...)
Affinity DataIC50: 310nMAssay Description:Inhibition of human PyK2 Y402 autophosphorylation expressed in 293T cells by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed