BDBM50301114 (2S,3S,5S)-methyl 3-(hydroxycarbamoyl)-2-(4-phenylpiperazine-1-carbonyl)-5-(pyrrolidine-1-carbonyloxy)piperidine-1-carboxylate::CHEMBL585886

SMILES COC(=O)N1C[C@H](C[C@@H]([C@H]1C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO)OC(=O)N1CCCC1

InChI Key InChIKey=KMMXFFDNBCQBEI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50301114   

Target72 kDa type IV collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301114((2S,3S,5S)-methyl 3-(hydroxycarbamoyl)-2-(4-phenyl...)
Affinity DataIC50: 613nMAssay Description:Inhibition of MMP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50301114((2S,3S,5S)-methyl 3-(hydroxycarbamoyl)-2-(4-phenyl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of ADAM-10More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301114((2S,3S,5S)-methyl 3-(hydroxycarbamoyl)-2-(4-phenyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301114((2S,3S,5S)-methyl 3-(hydroxycarbamoyl)-2-(4-phenyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301114((2S,3S,5S)-methyl 3-(hydroxycarbamoyl)-2-(4-phenyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301114((2S,3S,5S)-methyl 3-(hydroxycarbamoyl)-2-(4-phenyl...)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of HER-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed