BDBM50301098 4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl)pyridin-2-yl)ethyl)pyridin-2(1H)-one::CHEMBL565833

SMILES CCCNCc1ccc(CCn2ccc(OCc3ccc(F)cc3)cc2=O)nc1

InChI Key InChIKey=ONUBXRCAOBQBRS-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50301098   

TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 27nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of delta-type opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 7nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human ERG potassium channel 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mu-type opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of kappa-type opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of histamine H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of adenosine receptor A2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed