BDBM50300779 9-(3-hydroxypropyl)-6-((2'-isopropylbiphenyl-3-yl)methylamino)-9H-purine-2-carbonitrile::CHEMBL569883

SMILES CC(C)c1ccccc1-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1

InChI Key InChIKey=ICUVCOAXOLUVPJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300779   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California

Curated by ChEMBL
LigandPNGBDBM50300779(9-(3-hydroxypropyl)-6-((2'-isopropylbiphenyl-3-yl)...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50300779(9-(3-hydroxypropyl)-6-((2'-isopropylbiphenyl-3-yl)...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50300779(9-(3-hydroxypropyl)-6-((2'-isopropylbiphenyl-3-yl)...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed