BDBM50300750 4-(3-bromophenyl)-3-cyano-1,2,5-oxadiazole 2-oxide::CHEMBL574579

SMILES [O-][n+]1onc(c1C#N)-c1cccc(Br)c1

InChI Key InChIKey=HEWUYHLEGWWDBV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300750   

TargetThioredoxin reductase 1, cytoplasmic(Rat)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300750(4-(3-bromophenyl)-3-cyano-1,2,5-oxadiazole 2-oxide...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of rat recombinant TrxR1 after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetThioredoxin glutathione reductase(Blood fluke)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300750(4-(3-bromophenyl)-3-cyano-1,2,5-oxadiazole 2-oxide...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300750(4-(3-bromophenyl)-3-cyano-1,2,5-oxadiazole 2-oxide...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant GR after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed