BDBM50300748 4-(4-bromophenyl)-3-cyano-1,2,5-oxadiazole 2-oxide::CHEMBL585368

SMILES [O-][n+]1onc(c1C#N)-c1ccc(Br)cc1

InChI Key InChIKey=IJZDOWKMNHCYCN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300748   

TargetThioredoxin reductase 1, cytoplasmic(Rat)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300748(4-(4-bromophenyl)-3-cyano-1,2,5-oxadiazole 2-oxide...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of rat recombinant TrxR1 after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetThioredoxin glutathione reductase(Blood fluke)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300748(4-(4-bromophenyl)-3-cyano-1,2,5-oxadiazole 2-oxide...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300748(4-(4-bromophenyl)-3-cyano-1,2,5-oxadiazole 2-oxide...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant GR after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed