BDBM50300746 3-cyano-4-(4-(trifluoromethyl)phenyl)-1,2,5-oxadiazole 2-oxide::CHEMBL571712

SMILES [O-][n+]1onc(c1C#N)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=FCLXEDQPMBMSSA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300746   

TargetThioredoxin reductase 1, cytoplasmic(Rat)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300746(3-cyano-4-(4-(trifluoromethyl)phenyl)-1,2,5-oxadia...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of rat recombinant TrxR1 after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetThioredoxin glutathione reductase(Blood fluke)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300746(3-cyano-4-(4-(trifluoromethyl)phenyl)-1,2,5-oxadia...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300746(3-cyano-4-(4-(trifluoromethyl)phenyl)-1,2,5-oxadia...)
Affinity DataIC50: 4.53E+4nMAssay Description:Inhibition of human recombinant GR after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed