BDBM50300742 3-cyano-4-(3,4,5-trimethoxyphenyl)-1,2,5-oxadiazole 2-oxide::CHEMBL568961

SMILES COc1cc(cc(OC)c1OC)-c1no[n+]([O-])c1C#N

InChI Key InChIKey=UYUFUMMZDCUJKO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300742   

TargetThioredoxin reductase 1, cytoplasmic(Rat)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300742(3-cyano-4-(3,4,5-trimethoxyphenyl)-1,2,5-oxadiazol...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of rat recombinant TrxR1 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThioredoxin glutathione reductase(Blood fluke)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300742(3-cyano-4-(3,4,5-trimethoxyphenyl)-1,2,5-oxadiazol...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300742(3-cyano-4-(3,4,5-trimethoxyphenyl)-1,2,5-oxadiazol...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant GR after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed