BDBM50300547 2,3,9,10-Tetrahydroxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium chloride::CHEMBL572918

SMILES Oc1cc2CCn3cc4c(ccc(O)c4=[OH+])cc3-c2cc1O

InChI Key InChIKey=GZQCOOSAYGQCDU-UHFFFAOYSA-O

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300547   

TargetCell division control protein 42 homolog(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300547(2,3,9,10-Tetrahydroxy-5,6-dihydro-isoquino[3,2-a]i...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300547(2,3,9,10-Tetrahydroxy-5,6-dihydro-isoquino[3,2-a]i...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed