BDBM50300237 (R)-5-(2-Cyclohexylethyl)-5-(cyclohexylmethyl)-3-[4-(2-oxo-4(S)-propylimidazolidin-1-yl)methyl]benzyl-2-iminohydantoin::CHEMBL583875

SMILES CCC[C@H]1CN(Cc2ccc(CN3C(N)=NC(CCC4CCCCC4)(CC4CCCCC4)C3=O)cc2)C(=O)N1

InChI Key InChIKey=SILGEXOUELDSRZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300237   

TargetBeta-secretase 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50300237((R)-5-(2-Cyclohexylethyl)-5-(cyclohexylmethyl)-3-[...)
Affinity DataIC50: 27nMAssay Description:Inhibition of BACE1 mediated human Swedish amyloid precursor protein peptide hydrolysis by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed