BDBM50300236 CHEMBL568942::rac-3-[(3-Butylureido)methyl]benzyl-5-cyclohexylethyl-5-cyclohexylmethyl-2-iminohydantoin

SMILES CCCCNC(=O)NCc1ccc(CN2C(N)=NC(CCC3CCCCC3)(CC3CCCCC3)C2=O)cc1

InChI Key InChIKey=FXIAVDHDQYLVCR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300236   

TargetBeta-secretase 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50300236(rac-3-[(3-Butylureido)methyl]benzyl-5-cyclohexylet...)
Affinity DataIC50: 350nMAssay Description:Inhibition of BACE1 mediated human Swedish amyloid precursor protein peptide hydrolysis by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed