BDBM50300230 CHEMBL584963::rac-3-{4-[3-(4-Cyanophenyl)-ureidomethyl]benzyl}-5-isobutyl-5-methyl-2-iminohydantoin

SMILES CC(C)CC1(C)N=C(N)N(Cc2ccc(CNC(=O)Nc3ccc(cc3)C#N)cc2)C1=O

InChI Key InChIKey=CTKHUQYUPSHMQE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300230   

TargetBeta-secretase 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50300230(rac-3-{4-[3-(4-Cyanophenyl)-ureidomethyl]benzyl}-5...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of BACE1 mediated human Swedish amyloid precursor protein peptide hydrolysis by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed