BDBM50300081 1-(2-fluoroethyl)-3-(4-(4-morpholino-1-(2,2,2-trifluoroethyl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)urea::CHEMBL574234

SMILES FCCNC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(CC(F)(F)F)c2n1

InChI Key InChIKey=ZAEPCTWTCFBKRF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50300081   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300081(1-(2-fluoroethyl)-3-(4-(4-morpholino-1-(2,2,2-trif...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of FLAG-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50300081(1-(2-fluoroethyl)-3-(4-(4-morpholino-1-(2,2,2-trif...)
Affinity DataIC50: 314nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300081(1-(2-fluoroethyl)-3-(4-(4-morpholino-1-(2,2,2-trif...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of mTOR in HEK293 cells by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50300081(1-(2-fluoroethyl)-3-(4-(4-morpholino-1-(2,2,2-trif...)
Affinity DataIC50: 315nMAssay Description:Inhibition of PI3Kalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed