BDBM50298108 3-(4-Fluoro-phenyl)-2-(4,4,4-trifluoro-3-mercapto-butyrylamino)-propionic acid::CHEMBL551145

SMILES OC(=O)C(Cc1ccc(F)cc1)NC(=O)CC(S)C(F)(F)F

InChI Key InChIKey=PGJZLTNQRTXDPB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50298108   

TargetAngiotensin-converting enzyme(Human)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298108(3-(4-Fluoro-phenyl)-2-(4,4,4-trifluoro-3-mercapto-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeprilysin [1-24](Pig)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298108(3-(4-Fluoro-phenyl)-2-(4,4,4-trifluoro-3-mercapto-...)
Affinity DataIC50: 230nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298108(3-(4-Fluoro-phenyl)-2-(4,4,4-trifluoro-3-mercapto-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed