BDBM50297445 CHEMBL561483::N-hydroxy-7,7-bis(7-methoxy-1H-indol-3-yl)heptanamide

SMILES COc1cccc2c(c[nH]c12)C(CCCCCC(=O)NO)c1c[nH]c2c(OC)cccc12

InChI Key InChIKey=FSLXJUDEBBIVKO-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50297445   

TargetHistone deacetylase 1(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297445(N-hydroxy-7,7-bis(7-methoxy-1H-indol-3-yl)heptanam...)
Affinity DataIC50: 83nMAssay Description:Inhibition of human HDAC1 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297445(N-hydroxy-7,7-bis(7-methoxy-1H-indol-3-yl)heptanam...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human HDAC2 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297445(N-hydroxy-7,7-bis(7-methoxy-1H-indol-3-yl)heptanam...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human HDAC3 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297445(N-hydroxy-7,7-bis(7-methoxy-1H-indol-3-yl)heptanam...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human HDAC4 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297445(N-hydroxy-7,7-bis(7-methoxy-1H-indol-3-yl)heptanam...)
Affinity DataIC50: 311nMAssay Description:Inhibition of human HDAC5 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297445(N-hydroxy-7,7-bis(7-methoxy-1H-indol-3-yl)heptanam...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human HDAC6 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297445(N-hydroxy-7,7-bis(7-methoxy-1H-indol-3-yl)heptanam...)
Affinity DataIC50: 420nMAssay Description:Inhibition of human HDAC7 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297445(N-hydroxy-7,7-bis(7-methoxy-1H-indol-3-yl)heptanam...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human HDAC8 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297445(N-hydroxy-7,7-bis(7-methoxy-1H-indol-3-yl)heptanam...)
Affinity DataIC50: 340nMAssay Description:Inhibition of human HDAC9 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297445(N-hydroxy-7,7-bis(7-methoxy-1H-indol-3-yl)heptanam...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human HDAC10 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed