BDBM50297427 1-(5-(3,4-dimethoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)ethanone::4,5-Dihydro-(1H)-pyrazole derivative, 1m::CHEMBL562142

SMILES COc1ccc(cc1OC)C1CC(=NN1C(C)=O)c1ccccc1

InChI Key InChIKey=FOIXJKJVLPARQZ-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50297427   

TargetAmine oxidase [flavin-containing] A(Human)
UniversitÀ

LigandPNGBDBM50297427(4,5-Dihydro-(1H)-pyrazole derivative, 1m | CHEMBL5...)
Affinity DataIC50: 10nMAssay Description:Monoamine oxidase inhibitory activity of derivatives of 4, dihydro-(1H)-pyrazole.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
UniversitÀ

LigandPNGBDBM50297427(4,5-Dihydro-(1H)-pyrazole derivative, 1m | CHEMBL5...)
Affinity DataIC50: 2.50E+4nMAssay Description:Monoamine oxidase inhibitory activity of derivatives of 4, dihydro-(1H)-pyrazole.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
UniversitÀ

LigandPNGBDBM50297427(4,5-Dihydro-(1H)-pyrazole derivative, 1m | CHEMBL5...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of MAOBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
Indo-Soviet Friendship College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50297427(4,5-Dihydro-(1H)-pyrazole derivative, 1m | CHEMBL5...)
Affinity DataIC50: 8.37E+4nMAssay Description:Inhibition of bovine Xanthine oxidase assessed as decrease in uric acid production preincubated at 293 nM of compound for 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed