BDBM50297164 3-[3-(2-Carbamoylphenylamino)phenyl]acrylic acidmethyl ester::CHEMBL558854

SMILES COC(=O)\C=C\c1cccc(Nc2ccccc2C(N)=O)c1

InChI Key InChIKey=HUNMIQLXXMJMMT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50297164   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50297164(3-[3-(2-Carbamoylphenylamino)phenyl]acrylic acidme...)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of human recombinant SIRT1 by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50297164(3-[3-(2-Carbamoylphenylamino)phenyl]acrylic acidme...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50297164(3-[3-(2-Carbamoylphenylamino)phenyl]acrylic acidme...)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of human recombinant SIRT1 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed