BDBM50297153 (Z)-5-(4-methoxybenzylidene)imidazolidine-2,4-dione::5-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-imidazolidine-2,4-dione::CHEMBL38043

SMILES COc1ccc(\C=C2/NC(=O)NC2=O)cc1

InChI Key InChIKey=XLTKBDZXXGQCSC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50297153   

LigandPNGBDBM50297153(5-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-imidazol...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length recombinant human GST-tagged DYRK1B expressed in insect cells using KKISGRLSPIMTEQ-NH2 as substrate incubated for 15 mins i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
LigandPNGBDBM50297153(5-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-imidazol...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A catalytic domain expressed in Escherichia coli BL21(DE3) cells using KKISGRLSPIMTEQ-NH2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50297153(5-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-imidazol...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged CLK1 catalytic domain (129 to 484 residues) expressed in Escherichia coli using GRSRSRSRSRSRSRSR as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50297153(5-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-imidazol...)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of recombinant GSK3-beta by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed