BDBM50297148 (R)-3-Methoxy-7-propyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL539450

SMILES CCC[C@@H]1CNc2c(sc3ccc(OC)cc23)C(=O)N1

InChI Key InChIKey=XXIHHKWKHPBCOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297148   

TargetMAP kinase-activated protein kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297148((R)-3-Methoxy-7-propyl-5,6,7,8-tetrahydro-10-thia-...)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297148((R)-3-Methoxy-7-propyl-5,6,7,8-tetrahydro-10-thia-...)
Affinity DataIC50: 5.45E+3nMAssay Description:Inhibition of MK2 in human U937 cells assessed as blockade of LPS-stimulated TNFalpha productionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed