BDBM50297146 (R)-3-Isobutoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL563308

SMILES CC(C)COc1ccc2sc3c(NC[C@@H](C)NC3=O)c2c1

InChI Key InChIKey=JJQNDXCUJRPPDT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50297146   

TargetMAP kinase-activated protein kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297146((R)-3-Isobutoxy-7-methyl-5,6,7,8-tetrahydro-10-thi...)
Affinity DataIC50: 30nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297146((R)-3-Isobutoxy-7-methyl-5,6,7,8-tetrahydro-10-thi...)
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297146((R)-3-Isobutoxy-7-methyl-5,6,7,8-tetrahydro-10-thi...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of MK2 in human U937 cells assessed as blockade of LPS-stimulated TNFalpha productionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed