BDBM50296986 (R)-2-(8-(4-fluoro-N-methylphenylsulfonamido)-6,7,8,9-tetrahydro-5H-pyrazino[2,3-b]indol-5-yl)acetic acid::CHEMBL556849

SMILES CN([C@@H]1CCc2c(C1)c1nccnc1n2CC(O)=O)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=TWQRVSJZLRCHNE-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50296986   

TargetProstaglandin D2 receptor 2(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296986((R)-2-(8-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataIC50: 96nMAssay Description:Displacement of [3H]PGD2 from human prostaglandin D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296986((R)-2-(8-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataIC50: 127nMAssay Description:Displacement of [3H]PGD2 from human prostaglandin D2 receptor in presence of human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296986((R)-2-(8-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataIC50: 3.78E+4nMAssay Description:Displacement of [3H]PGD2 from prostaglandin D1 receptor in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296986((R)-2-(8-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]SQ-29548 from thromboxane receptor in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296986((R)-2-(8-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]iloprost from human prostacyclin receptor expressed in human 293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296986((R)-2-(8-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296986((R)-2-(8-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296986((R)-2-(8-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed