BDBM50296982 (R)-2-(9-(4-fluoro-N-methylphenylsulfonamido)-7,8,9,10-tetrahydropyrido[2,1-a]isoindol-6-yl)acetic acid::CHEMBL564845

SMILES CN([C@@H]1CCc2c(CC(O)=O)n3ccccc3c2C1)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=SNFXVJPZRORJQP-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50296982   

TargetProstaglandin D2 receptor 2(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296982((R)-2-(9-(4-fluoro-N-methylphenylsulfonamido)-7,8,...)
Affinity DataIC50: 61nMAssay Description:Displacement of [3H]PGD2 from human prostaglandin D2 receptor in presence of human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296982((R)-2-(9-(4-fluoro-N-methylphenylsulfonamido)-7,8,...)
Affinity DataIC50: 94nMAssay Description:Displacement of [3H]PGD2 from human prostaglandin D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296982((R)-2-(9-(4-fluoro-N-methylphenylsulfonamido)-7,8,...)
Affinity DataIC50: 3.10E+4nMAssay Description:Displacement of [3H]PGD2 from prostaglandin D1 receptor in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296982((R)-2-(9-(4-fluoro-N-methylphenylsulfonamido)-7,8,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]iloprost from human prostacyclin receptor expressed in human 293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296982((R)-2-(9-(4-fluoro-N-methylphenylsulfonamido)-7,8,...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296982((R)-2-(9-(4-fluoro-N-methylphenylsulfonamido)-7,8,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296982((R)-2-(9-(4-fluoro-N-methylphenylsulfonamido)-7,8,...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed