BDBM50296845 2-(1-(3-chloro-4-fluorophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid::CHEMBL551274

SMILES Cc1c(CC(O)=O)c2cccnc2n1S(=O)(=O)c1ccc(F)c(Cl)c1

InChI Key InChIKey=RXMROYPWKDYKEM-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50296845   

TargetProstaglandin D2 receptor 2(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296845(2-(1-(3-chloro-4-fluorophenylsulfonyl)-2-methyl-1H...)
Affinity DataIC50: 50nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296845(2-(1-(3-chloro-4-fluorophenylsulfonyl)-2-methyl-1H...)
Affinity DataIC50: 311nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296845(2-(1-(3-chloro-4-fluorophenylsulfonyl)-2-methyl-1H...)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed