BDBM50296534 6-methoxy-N-(5-(3-(trifluoromethyl)benzyl)thiazol-2-yl)-2-naphthamide::CHEMBL564822

SMILES COc1ccc2cc(ccc2c1)C(=O)Nc1ncc(Cc2cccc(c2)C(F)(F)F)s1

InChI Key InChIKey=RQDMDMIVEPJOKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296534   

TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296534(6-methoxy-N-(5-(3-(trifluoromethyl)benzyl)thiazol-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296534(6-methoxy-N-(5-(3-(trifluoromethyl)benzyl)thiazol-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed