BDBM50296445 2-(4-fluorophenylamino)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one::CHEMBL538196

SMILES Fc1ccc(NC2=NC(=O)C(S2)=Cc2cccs2)cc1

InChI Key InChIKey=NCDWDTOWQJGHJG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296445   

TargetM-phase inducer phosphatase 1(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296445(2-(4-fluorophenylamino)-5-(thiophen-2-ylmethylene)...)
Affinity DataIC50: 3.07E+4nMAssay Description:Inhibition of N-terminal 6xHis-tagged human Cdc25A (336-523) catalytic domain expressed in Escherichia coli after 20 mins by fluorescent plate reader...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296445(2-(4-fluorophenylamino)-5-(thiophen-2-ylmethylene)...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed