BDBM50296003 4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid::CHEMBL550795

SMILES OC(=O)c1ccc(cc1)-c1c[nH]c2ncc(cc12)-c1ccccc1

InChI Key InChIKey=KSFDVNIKNYXUIP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50296003   

TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50296003(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic ...)
Affinity DataIC50: 40nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50296003(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic ...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiologica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50296003(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic ...)
Affinity DataIC50: 182nMAssay Description:Inhibition of recombinant human His-tagged AXL expressed in insect cells after 60 mins by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50296003(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic ...)
Affinity DataIC50: 200nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed