BDBM50295632 CHEMBL541941::rac-3-Chloro-4'-(1-imidazol-1-yl-propyl)-biphenyl-4-ol

SMILES CCC(c1ccc(cc1)-c1ccc(O)c(Cl)c1)n1ccnc1

InChI Key InChIKey=IZQNXPIWJTTZEN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295632   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50295632(rac-3-Chloro-4'-(1-imidazol-1-yl-propyl)-biphenyl-...)
Affinity DataIC50: 217nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50295632(rac-3-Chloro-4'-(1-imidazol-1-yl-propyl)-biphenyl-...)
Affinity DataIC50: 91nMAssay Description:Inhibition of recombinant CYP3A4 expressed in baculovirus-infected insect microsome at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed