BDBM50295523 CHEMBL562380::N-(4-Bromophenyl)-2-[5-(4-methoxybenzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]-acetamide

SMILES COc1ccc(Cc2cc(C)nn(CC(=O)Nc3ccc(Br)cc3)c2=O)cc1

InChI Key InChIKey=CMDXHAKUWAHYGG-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50295523   

TargetfMet-Leu-Phe receptor(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295523(N-(4-Bromophenyl)-2-[5-(4-methoxybenzyl)-3-methyl-...)
Affinity DataEC50:  4.30E+3nMAssay Description:Agonist activity at FPR1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295523(N-(4-Bromophenyl)-2-[5-(4-methoxybenzyl)-3-methyl-...)
Affinity DataEC50:  4.30E+3nMAssay Description:Agonist activity at FPR1 in human neutrophiles by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295523(N-(4-Bromophenyl)-2-[5-(4-methoxybenzyl)-3-methyl-...)
Affinity DataEC50:  1.31E+4nMAssay Description:Agonist activity at FPRL1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295523(N-(4-Bromophenyl)-2-[5-(4-methoxybenzyl)-3-methyl-...)
Affinity DataEC50:  1.31E+4nMAssay Description:Agonist activity at FPRL1 in human neutrophiles by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295523(N-(4-Bromophenyl)-2-[5-(4-methoxybenzyl)-3-methyl-...)
Affinity DataEC50:  2.40E+3nMAssay Description:Agonist activity at FPRL1 expressed in human HL60 cells assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295523(N-(4-Bromophenyl)-2-[5-(4-methoxybenzyl)-3-methyl-...)
Affinity DataEC50:  3.80E+3nMAssay Description:Agonist activity at FPR2 (unknown origin) by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed