BDBM50295468 1-(2,6-Difluorobenzoyl)-3-(9H-fluoren-9-yl)-urea::CHEMBL525897

SMILES Fc1cccc(F)c1C(=O)NC(=O)NC1c2ccccc2-c2ccccc12

InChI Key InChIKey=KZLSEPOWGFQHNH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295468   

TargetPeptidyl-prolyl cis-trans isomerase A(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50295468(1-(2,6-Difluorobenzoyl)-3-(9H-fluoren-9-yl)-urea |...)
Affinity DataIC50: 263nMAssay Description:Inhibition of peptidyl-prolyl isomerase activity of Cyclophilin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50295468(1-(2,6-Difluorobenzoyl)-3-(9H-fluoren-9-yl)-urea |...)
Affinity DataIC50: 263nMAssay Description:Inhibition of CypA (unknown origin) assessed as peptidyl-prolyl cis-trans isomerase activity using N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed