BDBM50295242 11-(2-chloro-6-fluorophenyl)-3,3-dimethyl-1-oxo-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepine-8-carboxylic acid::CHEMBL563633

SMILES CC1(C)CC(=O)C2C(Nc3cc(ccc3N=C2C1)C(O)=O)c1c(F)cccc1Cl

InChI Key InChIKey=LGUKSKUMIRVUCO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295242   

TargetNeuromedin-B receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50295242(11-(2-chloro-6-fluorophenyl)-3,3-dimethyl-1-oxo-2,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed