BDBM50294722 4-((2-chlorobenzyl)(1-(4,5-dimethyl-4H-1,2,4-triazol-3-yl)butyl)amino)-2-chlorobenzonitrile::CHEMBL555562

SMILES CCCC(N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1)c1nnc(C)n1C

InChI Key InChIKey=XBBPOZPLTBYZHN-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50294722   

TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294722(4-((2-chlorobenzyl)(1-(4,5-dimethyl-4H-1,2,4-triaz...)
Affinity DataIC50: 50nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294722(4-((2-chlorobenzyl)(1-(4,5-dimethyl-4H-1,2,4-triaz...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at progesterone receptor in human T47D cells by alkaline phosphatase release based reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294722(4-((2-chlorobenzyl)(1-(4,5-dimethyl-4H-1,2,4-triaz...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed