BDBM50294551 1-Chloro-3-methyl-5-phenethyl-5,6,7,12-tetrahydro-2,5,12-triaza-dibenzo[a,e]azulene::CHEMBL560245

SMILES Cc1cc2N(CCc3ccccc3)CCc3c([nH]c4ccccc34)-c2c(Cl)n1

InChI Key InChIKey=VSCNEMQPXDDNNG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50294551   

TargetInsulin receptor(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294551(1-Chloro-3-methyl-5-phenethyl-5,6,7,12-tetrahydro-...)
Affinity DataIC50: 3.05E+4nMAssay Description:Inhibition of human recombinant IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294551(1-Chloro-3-methyl-5-phenethyl-5,6,7,12-tetrahydro-...)
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of 6xHis-tagged human NPM-ALK expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294551(1-Chloro-3-methyl-5-phenethyl-5,6,7,12-tetrahydro-...)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of recombinant IGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294551(1-Chloro-3-methyl-5-phenethyl-5,6,7,12-tetrahydro-...)
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of recombinant METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294551(1-Chloro-3-methyl-5-phenethyl-5,6,7,12-tetrahydro-...)
Affinity DataIC50: 3.35E+4nMAssay Description:Inhibition of recombinant JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed