BDBM50294549 1-Chloro-3-methyl-5-phenethyl-5,6,7,12-tetrahydro-4,5,12-triaza-dibenzo[a,e]azulene::CHEMBL563080

SMILES Cc1cc(Cl)c2-c3[nH]c4ccccc4c3CCN(CCc3ccccc3)c2n1

InChI Key InChIKey=FKSBROWWHIJTKO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50294549   

TargetALK tyrosine kinase receptor(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294549(1-Chloro-3-methyl-5-phenethyl-5,6,7,12-tetrahydro-...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of 6xHis-tagged human NPM-ALK expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294549(1-Chloro-3-methyl-5-phenethyl-5,6,7,12-tetrahydro-...)
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibition of human recombinant IRKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294549(1-Chloro-3-methyl-5-phenethyl-5,6,7,12-tetrahydro-...)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of recombinant METMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294549(1-Chloro-3-methyl-5-phenethyl-5,6,7,12-tetrahydro-...)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of recombinant IGFR1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294549(1-Chloro-3-methyl-5-phenethyl-5,6,7,12-tetrahydro-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant JAK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed