BDBM50294545 4-[2-(9-Bromo-1-iodo-6,7-dihydro-12H-4,5,12-triaza-dibenzo[a,e]azulen-5-yl)-ethyl]-phenol::CHEMBL557491

SMILES Oc1ccc(CCN2CCc3c([nH]c4ccc(Br)cc34)-c3c(I)ccnc23)cc1

InChI Key InChIKey=PNLCKHKUOXMMDD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50294545   

TargetInsulin receptor(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294545(4-[2-(9-Bromo-1-iodo-6,7-dihydro-12H-4,5,12-triaza...)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of human recombinant IRKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294545(4-[2-(9-Bromo-1-iodo-6,7-dihydro-12H-4,5,12-triaza...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of 6xHis-tagged human NPM-ALK expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294545(4-[2-(9-Bromo-1-iodo-6,7-dihydro-12H-4,5,12-triaza...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of recombinant METMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed