BDBM50294184 CHEMBL561640::N-(4-chlorophenyl)-2-phenoxypropanamide::N-(4-chlorophenyl)-2-phenoxypropanamide, A::N-(4-chlorophenyl)-2-phenoxypropanamide, Compound A

SMILES CC(Oc1ccccc1)C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=HHNBSZFQIIWTAP-UHFFFAOYSA-N

Data  8 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50294184   

TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Brandeis University

LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInosine-5-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataIC50: 3.30E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataIC50: 3.30E+3nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase(Helicobacter pylori (strain G27))
Brandeis University

LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataIC50: 2.20E+3nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase(Borrelia burgdorferi)
Brandeis University

LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataIC50: 1.40E+3nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase(Streptococcus pyogenes (Firmicutes))
Brandeis University

LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataIC50: 9.60E+4nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human recombinant IMPDH1 expressed in Escherichia coli guaB assessed as NADH production by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Brandeis University

LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human recombinant IMPDH2 expressed in Escherichia coli guaB assessed as NADH production by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli TX685 assessed as NADH production by fluorescence assay in absen...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataEC50:  3.30E+3nMAssay Description:Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli guaB assessed as NADH production by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed