BDBM50294043 2-(3-Cyclohexyl-3-methylthioureido)thiophene-3-carboxylic Acid::CHEMBL554602

SMILES CN(C1CCCCC1)C(=S)Nc1sccc1C(O)=O

InChI Key InChIKey=MNLJTQOGIGSVKR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294043   

TargetMultidrug resistance-associated protein 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50294043(2-(3-Cyclohexyl-3-methylthioureido)thiophene-3-car...)
Affinity DataIC50: 4.51E+3nMAssay Description:Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50294043(2-(3-Cyclohexyl-3-methylthioureido)thiophene-3-car...)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of BCRP expressed in MCF7 MX cells by Hoechst 33342 stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed