BDBM50293771 2-(3-aminopyrrolidin-1-yl)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylic acid::CHEMBL564345

SMILES NC1CCN(C1)c1nc2cc(ccc2n1Cc1ccccc1C(F)(F)F)C(O)=O

InChI Key InChIKey=CWWOLUDEFWSPOS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293771   

TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293771(2-(3-aminopyrrolidin-1-yl)-1-(2-(trifluoromethyl)b...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF3B(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293771(2-(3-aminopyrrolidin-1-yl)-1-(2-(trifluoromethyl)b...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Kif3BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin heavy chain isoform 5A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293771(2-(3-aminopyrrolidin-1-yl)-1-(2-(trifluoromethyl)b...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of nKHCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed