BDBM50293631 4-bromo-N-(3-bromo-4-(2-(2-methylpyrrolidin-1-yl)ethoxy)phenethyl)thiophene-2-carboxamide::CHEMBL559843

SMILES CC1CCCN1CCOc1ccc(CCNC(=O)c2cc(Br)cs2)cc1Br

InChI Key InChIKey=VLJYRARAGISBAK-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50293631   

TargetHistamine H3 receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50293631(4-bromo-N-(3-bromo-4-(2-(2-methylpyrrolidin-1-yl)e...)
Affinity DataIC50: 710nMAssay Description:Displacement of [3H]SMT from human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50293631(4-bromo-N-(3-bromo-4-(2-(2-methylpyrrolidin-1-yl)e...)
Affinity DataIC50: 750nMAssay Description:Displacement of [3H]SMT from human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50293631(4-bromo-N-(3-bromo-4-(2-(2-methylpyrrolidin-1-yl)e...)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]SMT from human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50293631(4-bromo-N-(3-bromo-4-(2-(2-methylpyrrolidin-1-yl)e...)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]SMT from human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed