BDBM50293249 5-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimidin-2-ylamino)isophthalamide::CHEMBL460600

SMILES NC(=O)c1cc(Nc2nccc(Nc3c4OCOc4ccc3Cl)n2)cc(c1)C(N)=O

InChI Key InChIKey=MCPINKCJNXYHSN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293249   

TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293249(5-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50: 77nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293249(5-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed